IHOP ecology

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J Couns Psychol. 2015 Apr;62(2):289-302.
Construction and initial validation of the Gendered Racial Microaggressions Scale for Black women.
Lewis JA1, Neville HA2.
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The purpose of this study was to develop a measure of gendered racial microaggressions (i.e., subtle and everyday verbal, behavioral, and environmental expressions of oppression based on the intersection of one’s race and gender) experienced by Black women by applying an intersectionality framework to Essed’s (1991) theory of gendered racism and Sue, Capodilupo, et al.’s (2007) model of racial microaggressions. The Gendered Racial Microaggressions Scale (GRMS), was developed to assess both frequency and stress appraisal of microaggressions, in 2 separate studies. After the initial pool of GRMS items was developed, we received input from a community-based focus group of Black women and an expert panel. In Study 1, an exploratory factor analysis using a sample of 259 Black women resulted in a multidimensional scale with 4 factors as follows: (a) Assumptions of Beauty and Sexual Objectification, (b) Silenced and Marginalized, (c) Strong Black Woman Stereotype, and (d) Angry Black Woman Stereotype. In Study 2, results of confirmatory factor analyses using an independent sample of 210 Black women suggested that the 4-factor model was a good fit of the data for both the frequency and stress appraisal scales. Supporting construct validity, the GRMS was positively related to the Racial and Ethnic Microaggressions Scale (Nadal, 2011) and the Schedule of Sexist Events (Klonoff & Landrine, 1995). In addition, the GRMS was significantly related to psychological distress, such that greater perceived gendered racial microaggressions were related to greater levels of reported psychological distress. Implications for future research and practice are discussed. (PsycINFO Database Record
(c) 2015 APA, all rights reserved).
PMID: 25867696 [PubMed – as supplied by publisher]
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Nuclear receptors in transgenerational epigenetic inheritance.
Ozgyin L1, Erdős E1, Bojcsuk D1, Balint BL2.
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Nuclear Receptors are ligand-activated transcription factors that translate information about the lipid environment into specific genetic programs, a property that renders them good candidates to be mediators of rapid adaptation changes of a species. Lipid-based morphogens, endocrine hormones, fatty acids and xenobiotics might act through this class of transcription factors making them regulators able to fine-tune physiological processes. Here we review the basic concepts and current knowledge on the process whereby small molecules act through nuclear receptors and contribute to transgenerational changes. Several molecules shown to cause transgenerational changes like phthalates, BPA, nicotine, tributylin bind and activate nuclear receptors like ERs, androgen receptors, glucocorticoid receptors or PPARγ. A specific subset of observations involving nuclear receptors has focused on the effects of environmental stress or maternal behaviour on the development of transgenerational traits. While these effects do not involve environmental ligands, they change the expression levels of Estrogen and glucocorticoid receptors of the second generation and consequently initiate an altered genetic program in the second generation. In this review we summarize the available literature about the role of nuclear receptors in transgenerational inheritance.
Copyright © 2015 Elsevier Ltd. All rights reserved.
Epigenetic; Estrogen; Glucocorticoids; Nuclear receptors; Transgenerational

About garyskeete

ASHWORTH MEDICINE-Professional Medical Assisting, Doctor of Science,Legal Assistant Diploma BSc Criminal Justice PhD Computational Neuroscience MD DSC Epigenetics
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